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Animals diverge from common ancestry through
changes in their DNA, but what are the genes that control
morphology? In this landmark work, the author team led by
Dr. Sean Carroll presents the general principles of the
genetic basis of morphological change through a synthesis
of evolutionary biology with genetics and embryology. The
text first addresses the history of animal evolution, model
system developmental genetics, and genetic regulatory mechanisms
and then examines case studies of evolutionary change at
different genetic and morphological levels. An engaging
style, clear four-color illustrations (also available to
instructors on CD-ROM ) and up-to-date content all combine
to make this text a highly accessible synthesis of the field.
In this extensively revised second edition,
the authors delve into the latest discoveries, incorporating
new coverage of comparative genomics, molecular evolution
of regulatory proteins and elements, and microevolution
of animal development. This new edition also includes major
insights from recent genome studies, incorporates new findings
from evo-devo biology research, and adds a new chapter focusing
on models of variation, and divergence among closely related
species.
Sean Carroll is currently an investigator
of the Howard Hughes Medical Institute and Professor of
Molecular Biology and Genetics at the University of Wisconsin.
His research for the past twenty years has focused on the
genetics of animal development and evolution, and yielded
many original discoveries as to the mechanisms underlying
the making and evolution of animal form.
Jennifer Grenier is currently a senior
scientist at Mirus Bio Corporation in Madison, Wisconsin.
Her scientific interests include the evolution of development,
comparative genomics, and innovative technologies for functional
genomics research.
Scott Weatherbee is a research fellow
at the Memorial Sloan Kettering Cancer Center in New York
City. He studies the developmental genetics of limb formation
and patterning.
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