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Neuronal Man: The Biology of Mind
by Jean-Pierre Changeux

New York: Pantheon Books, 1985

Jean-Pierre Changeux is a world-famous neurobiologist. In an era when scientists have become specialists, he is one of the rare few who has not only disregarded interdisciplinary boundaries, but in fact, bridged them. Published originally in France, where it was a runaway bestseller for months, his Neuronal Man is our most wide-ranging and in-depth synthesis of the most current knowledge we have of the human brain -- a balance sheet of twenty years' worth of discoveries as revolutionary as those in atomic physics at the turn of the century or genetics in the fifties. But more than a guided tour of the fabulous universe of the human brain, the book presents the author's radical, groundbreaking hypothesis currently shaking up scientific circles: that there is no "mind" in man, nothing psychic, but rather only neurons, synapses, electricity, and chemistry.

The human cerebral cortex alone (the "rind" of the brain whose evolution culminates in man) contains at least 30 billion neurons (nerve cells). As Changeux explains, these communicate with each other at the level of gaps called synapses, which are so numerous that "if one counted a thousand of them each second, between 3,000 and 30,000 years would pass before they had all been numbered." Here he leads us through this complexity, with clarity, elegance of style, wit, and rigor. For the first time, the layperson can understand just what happens each millisecond in these 1400 grams of white and gray matter, and how these events generate other events and effects in the body.

Moving from this solid factual base, Dr. Changeux allows us to see the reasoning behind his theory of the biology of mind. Avoiding the traditional stumbling blocks on which attempts to link the mind and body usually collapse, his approach is neither "reductionist" nor "holistic"; that is, he neither reduces the functioning of the whole to that of its elements, nor sees a whole that is more than the sum of its parts. Rather, his method is global, systematic, and open. Each element of the human system contributes to its functioning as a whole, which in turn influences the characteristics and development of each element. The accent is on the highlighting of relations and interdependencies.

At once historical and didactic, scientific and philosophical, witty and shrewd, the story he tells is an exciting one of territorial struggles, conflicts of schools, retrogressions, and dazzling breakthroughs. We explore a wealth of fact, theory, lore, and speculation, which sets into relief the lines of research and attitudes that have influenced the development of our knowledge about the brain and mind. Along the way we consider a variety of questions: What weight should be attached to heredity, to environment, to training, and to stimulation, among other things, in determining how our brain works and how personality emerges, how the human becomes a feeling and social being? How did psychology grow away from its roots in neurology? What can the history of phrenology, and the implications that have been read into it, tell us about our social attitudes? How do the theories of Descartes, of Spinoza, of the ancient materialists and the modern psychiatrists, fit into the picture? How has the most recent technology affected scientists' thinking in this field?

In Neuronal Man, Dr. Changeux has allowed us to reconquer our internal space, on the basis of a new logic that allows us to grasp the logic of our brain from the outside, and that finally bridges the gap between the biological and the social, between body, mind, and soul.

An internationally renowned expert in his field, Dr. Jean-Pierre Changeux is professor of neurobiology at the College de France and director of the molecular neurobiology laboratory at the Institut Pasteur in Paris. Neuronal Man (originally published in France as L'Homme neuronal) won the Broquette-Gonin Literary Award from the Academie Francaise in 1983. Dr. Changeux currently lives in Paris.

 
   
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